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For example, Simo noted that higher levels of codeine – which is used in cold medicine – can be deposited in darker hair, which can trigger a lab positive and medical review.

All of this serves as backdrop for a much bigger effort taking place in the trucking industry – the creation of a national "clearinghouse" for drug and alcohol tests.

"But today over 90% of the diagnoses for medical marijuana prescriptions is for ‘chronic pain,’ not cancer or AIDS.

Thus detecting drug use via a screening process and disqualifying and applicant before they start work saves a company an average of ,000 per occurrence, Simo said – largely due to avoiding the costs noted in the three factors above.

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First, he noted that the "self-reported" use of drugs is rising pretty sharply, according to the National Institute on Drug Abuse (NIDA), climbing from 7.3% in 2013 to just under 9% by 2016.

"There’s been a creep up in the percentage in people self-reporting that in the last 30 days they took an illicit drug," he said.

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